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dropdown_menu_text_color=”#ffffff” mobile_menu_bg_color=”#474747″ mobile_menu_text_color=”#1f1f1f” admin_label=”Men\u00fa de anchura completa” _builder_version=”4.2.2″ menu_font=”Open Sans|600|||||||” menu_text_color=”#1f1f1f” background_color=”#eeeeee” text_orientation=”center”] [\/et_pb_fullwidth_menu][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”4.2.2″ background_color=”#ffffff”][et_pb_row admin_label=”row” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.2.2″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ use_border_color=”off” border_color=”#ffffff” border_style=”solid”]<\/p>\n
LINES OF RESEARCH<\/strong><\/p>\n Our research group is focused on the study of compounds of natural origin to search for new treatments in order to treat different diseases and on their biotechnological and pharmaceutical applications.<\/span><\/p>\n To do this, the group has the capacity to extract these molecules of natural origin, the tools for their analytical characterization, in silico screening techniques and cell and animal models to carry out functional activity tests. Finally, our group is capable of carrying out intervention trials in human volunteers.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ admin_label=”Fila” _builder_version=”4.2.2″ background_color=”rgba(0,0,0,0.05)” background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/unnamed2.png” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” admin_label=”Imagen” _builder_version=”4.2.2″ hover_enabled=”0″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” animation=”off” sticky=”off” always_center_on_mobile=”on”] [\/et_pb_image][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.2.2″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ use_border_color=”off” border_color=”#ffffff” border_style=”solid”]<\/p>\n Obesity and metabolic syndrome:<\/strong> This research line is focused on the search and identification of the bioactive molecules responsible for the management of energy homeostasis and the improvement of metabolic disturbances associated with obesity. This general objective is approached from different strategies: modulating pathways related to energy management and inducing the browning of white adipocyte and activating thermogenesis. This is carried out by using in silico screening techniques and pre-adipocyte cell lines that allow evaluating the capacity of the compounds to activate specific targets, as well as their effects on lipid metabolism and glucolipotoxicity-induced metabolic alterations in adipose tissue. The results of this research provide potential candidates for the elaboration of nutraceuticals that modulate energy metabolism and adipose tissue plasticity as therapeutic strategies against obesity. <\/span>Representative publication<\/span><\/a>.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ admin_label=”Fila” _builder_version=”4.2.2″ background_color=”rgba(0,0,0,0.05)” background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/fphar-12-625946-g001.gif” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” admin_label=”Imagen” _builder_version=”3.23″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” animation=”off” sticky=”off” always_center_on_mobile=”on”] [\/et_pb_image][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.2.2″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ use_border_color=”off” border_color=”#ffffff” border_style=”solid”]<\/p>\n Cancer: <\/strong><\/span><\/strong>Our group is aimed to find new compounds with antitumoral activity from vegetal and marine resources. We work in their obtention, isolation and in their mechanism of action using molecular and cellular biology techniques, cellular models and animal studies. This research topic has been recognized as \u201cProject with social interest\u201d by the Patronage Office of the Generalitat Valenciana. <\/span>Representavite publication<\/span><\/a>.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ admin_label=”Fila” _builder_version=”4.2.2″ background_color=”rgba(0,0,0,0.05)” background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/unnamed.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” admin_label=”Imagen” _builder_version=”4.2.2″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” animation=”off” sticky=”off” always_center_on_mobile=”on”] [\/et_pb_image][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.2.2″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid”]<\/p>\n Cosmetics: <\/strong><\/span><\/strong>Our group is involved in developing new in vitro techniques for the screening of biological activities with cosmetic uses, as antioxidant, antiaging or phtoprotective activities among others. We also are interested in looking for new compounds that can be used as new ingredients for the cosmetic industry. <\/span>\u00a0<\/span>\u00a0<\/span>Representetive publication.<\/span><\/a><\/p>\n <\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ admin_label=”Fila” _builder_version=”4.2.2″ background_color=”rgba(0,0,0,0.05)” background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/Javi-3.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” admin_label=”Imagen” _builder_version=”3.23″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” animation=”off” sticky=”off” always_center_on_mobile=”on”] [\/et_pb_image][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.2.2″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid”]<\/p>\n Antimicrobials: <\/strong><\/span><\/strong>New antimicrobial compounds from natural resources are also inside our scope. We are interested in the use of these compounds as new antibiotics and\/or preservatives for pharmaceutical, cosmetic, food and feed products. Our group is especially interested in their action against antibiotic resistant strains, which are one of the most important threats nowadays. <\/span>Representative publication.<\/span><\/a><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" LINES OF RESEARCH Our research group is focused on the study of compounds of natural origin to search for new treatments in order to treat different diseases and on their biotechnological and pharmaceutical applications. To do this, the group has the capacity to extract these molecules of natural origin, the tools for their analytical characterization, […]<\/p>\n","protected":false},"author":3782,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"[et_pb_section fb_built=\"1\" fullwidth=\"on\" custom_padding_last_edited=\"on|desktop\" admin_label=\"Secci\u00f3n\" _builder_version=\"3.22\" custom_padding_tablet=\"50px|0|50px|0\" custom_padding_phone=\"\" transparent_background=\"off\" padding_mobile=\"off\" make_fullwidth=\"off\" use_custom_width=\"off\" width_unit=\"on\"][et_pb_fullwidth_slider use_text_overlay=\"on\" admin_label=\"Control deslizante de anchura completa\" _builder_version=\"4.2.2\" custom_padding=\"197px||201px|||\" custom_padding_tablet=\"|||\" custom_padding_phone=\"|||\" auto=\"on\" auto_speed=\"3000\" remove_inner_shadow=\"off\" hide_content_on_mobile=\"off\" 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completa\" _builder_version=\"3.10.1\" menu_font=\"Open Sans|600|||||||\" menu_text_color=\"#1f1f1f\" background_color=\"#eeeeee\" text_orientation=\"center\"]\u00a0[\/et_pb_fullwidth_menu][\/et_pb_section][et_pb_section fb_built=\"1\" admin_label=\"section\" _builder_version=\"4.2.2\" background_color=\"#ffffff\"][et_pb_row admin_label=\"row\" _builder_version=\"3.25\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"4_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"Texto\" _builder_version=\"3.27.4\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\"]L\u00cdNEAS DE INVESTIGACI\u00d3N<\/strong>\r\n\r\nNuestro grupo de investigaci\u00f3n parte del estudio de los compuestos de origen natural para la b\u00fasqueda de nuevos tratamientos para diferentes enfermedades y aplicaciones biotecnol\u00f3gicas y farmac\u00e9uticas.<\/span>\r\n\r\nPara ello, el grupo cuenta con capacidad para la extracci\u00f3n de estas mol\u00e9culas de origen natural, las herramientas para su caracterizaci\u00f3n anal\u00edtica, las t\u00e9cnicas de cribado <\/span>in silico<\/span><\/i> y los modelos celulares y animales para llevar a cabo los ensayos de actividad funcional. Por \u00faltimo, nuestro grupo es capaz de llevar a cabo ensayos de intervenci\u00f3n en voluntarios humanos.<\/span>\r\n\r\n\u00a0\r\n\r\nLas actividades de investigaci\u00f3n del grupo se centran en cuatro grandes \u00e1reas:<\/span>\r\n\r\n\u00a0[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_4,3_4\" admin_label=\"Fila\" _builder_version=\"4.2.2\" background_color=\"rgba(0,0,0,0.05)\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/azul.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" admin_label=\"Imagen\" _builder_version=\"3.23\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\" animation=\"off\" sticky=\"off\" always_center_on_mobile=\"on\"]\u00a0[\/et_pb_image][\/et_pb_column][et_pb_column type=\"3_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"Texto\" _builder_version=\"3.27.4\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\"]Obesidad y s\u00edndrome metab\u00f3lico:<\/span><\/strong>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_4,3_4\" admin_label=\"Fila\" _builder_version=\"4.2.2\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" hover_enabled=\"0\" background_color=\"rgba(0,0,0,0.05)\"][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/fphar-12-625946-g001.gif\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" admin_label=\"Imagen\" _builder_version=\"3.23\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\" animation=\"off\" sticky=\"off\" always_center_on_mobile=\"on\"]\u00a0[\/et_pb_image][\/et_pb_column][et_pb_column type=\"3_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"Texto\" _builder_version=\"3.27.4\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\"]C\u00e1ncer:<\/strong> en esta l\u00ednea, nuestro grupo trabaja en la b\u00fasqueda de nuevos compuestos con actividad antitumoral a partir de fuentes vegetales y marinas, con especial atenci\u00f3n a los c\u00e1nceres de mama y colon. Este proyecto cuenta con el \u201cSello de inter\u00e9s social\u201d de la Oficina de Mecenazgo de la Generalitat Valenciana. <\/span>Publicaci\u00f3n representativa<\/span><\/a>.<\/span><\/strong>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_4,3_4\" admin_label=\"Fila\" _builder_version=\"4.2.2\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" hover_enabled=\"0\" background_color=\"rgba(0,0,0,0.05)\"][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/unnamed.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" admin_label=\"Imagen\" _builder_version=\"4.2.2\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\" animation=\"off\" sticky=\"off\" always_center_on_mobile=\"on\"]\u00a0[\/et_pb_image][\/et_pb_column][et_pb_column type=\"3_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"Texto\" _builder_version=\"3.27.4\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\"]Cosm\u00e9tica:<\/strong> en esta l\u00ednea trabajamos en dos frentes diferentes, el desarrollo de nuevos m\u00e9todos <\/span>in vitro<\/span><\/i> para el cribado de actividades biol\u00f3gicas de inter\u00e9s y la b\u00fasqueda y caracterizaci\u00f3n de nuevos ingredientes con actividades cosm\u00e9ticas de inter\u00e9s. <\/span>Publicaci\u00f3n representativa.<\/span><\/a><\/strong>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_4,3_4\" admin_label=\"Fila\" _builder_version=\"4.2.2\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" hover_enabled=\"0\" background_color=\"rgba(0,0,0,0.05)\"][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"http:\/\/grupo-ddmb.zeus.umh.es\/files\/2021\/12\/Javi-3.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" admin_label=\"Imagen\" _builder_version=\"3.23\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\" animation=\"off\" sticky=\"off\" always_center_on_mobile=\"on\"]\u00a0[\/et_pb_image][\/et_pb_column][et_pb_column type=\"3_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"Texto\" _builder_version=\"3.27.4\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\" use_border_color=\"off\" border_color=\"#ffffff\" border_style=\"solid\"]Antimicrobianos:<\/strong> dentro de este apartado nuestro grupo trabaja en el desarrollo de nuevos agentes antimicrobianos a partir de fuentes naturales con especial atenci\u00f3n a su acci\u00f3n sobre cepas de inter\u00e9s cl\u00ednico resistentes a antibi\u00f3ticos. <\/span>Publicaci\u00f3n representativa.<\/span><\/a><\/strong>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/grupo-ddmb.umh.es\/en\/wp-json\/wp\/v2\/pages\/1501"}],"collection":[{"href":"https:\/\/grupo-ddmb.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/grupo-ddmb.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/grupo-ddmb.umh.es\/en\/wp-json\/wp\/v2\/users\/3782"}],"replies":[{"embeddable":true,"href":"https:\/\/grupo-ddmb.umh.es\/en\/wp-json\/wp\/v2\/comments?post=1501"}],"version-history":[{"count":0,"href":"https:\/\/grupo-ddmb.umh.es\/en\/wp-json\/wp\/v2\/pages\/1501\/revisions"}],"wp:attachment":[{"href":"https:\/\/grupo-ddmb.umh.es\/en\/wp-json\/wp\/v2\/media?parent=1501"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}